The Food and Drug Administration on Tuesday cleared Philip Morris-owned Zyn nicotine pouches to be marketed as less harmful than cigarettes, giving the tobacco giant a major regulatory win as the Trump administration loosens restrictions on nicotine products.
The decision, first reported by Axios, allows 20 Zyn products to carry a modified-risk claim saying that switching from cigarettes to Zyn lowers the risk of mouth cancer, heart disease, lung cancer, stroke, emphysema and chronic bronchitis.
Zyn pouches contain nicotine but not tobacco. They are placed between a user’s gum and lip and have surged in popularity among conservatives, tech workers and others who promote them as a cleaner alternative to cigarettes and chewing tobacco or a productivity aid.
https://atm.amegroups.org/article/view/119609/html
2023 review found most animal tumor-initiation studies did not show nicotine increasing spontaneous tumor initiation, while tumor-progression results were inconsistent and hard to generalize
Smokeless tobacco is not “safe”, it’s addictive, may have oral/cardiovascular concerns, and long term data is limited, but cancer risk is likely far lower than chewing tobacco. Nicotine alone os not strongly established as cancer causing in humans, but biologically suspicious enough that “harmless” would be too strong.
There’s a reason the FDA is allowing Zyn to say there’s a difference now with “Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema, and chronic bronchitis”. People would do better to switch to Zyn than smoke or use dip. They’d do even better quitting, but people should understand there’s much higher risk with smoking and using chewing tobacco.