I personally can’t be sure, longest I’ve ever worn them on clinicals was 12 hours. I didn’t really feel they were that comfy that long. I did more EMT work and that required a different shoe. I had 24 hour shifts there. So I just used cute leather boots and they stayed outside my house cus they got gross. I felt more comfy and support in proper footwear personally. Kind of the same when in the military and deployed.

But everyone is different.